MS infektion aiheuttama?

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soijuv
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Liittynyt:Ke Tammi 21, 2009 14:16
MS infektion aiheuttama?

Viesti Kirjoittaja soijuv » Ti Loka 02, 2012 20:53

Allaolevassa artikkelissa esitetään näkemys MS-taudin oireiden johtuvan bakteereista esim. keuhkoklamydiasta ja sen hoitoon tulisi käyttää antibiootteja. Lukuisilla Borrelioosia sairastavilla on borrelia-bakteerin lisäksi keuhkoklamydia sekä mykoplasma. Useat saavat Borrelioosin sijaan MS diagnoosin.

MS Cure?

from Suzanne Stuttman
W Redding, CT

http://www.abc.net.au/catalyst/stories/3572695.htm

Thursday, 23 August 2012



Some doctors contend that Multiple Sclerosis (MS) is triggered by an infection, which could be cured with antibiotics.

TRANSCRIPT
Narration
Is it possible that Multiple Sclerosis can be cured? According to these medical mavericks, the answer is yes.

Dr Paul Thibault
This is a paradigm shift in the way we understand the disease.

Narration
They argue that an infection is what triggers the disease.

Dr David Wheldon
The immune system sort of knows it’s there but can't do much about it.

Dr Maryanne Demasi
Incredibly, the treatment has been right under our noses. Here, I explore an unpopular medical theory that has been flying under the radar until now.

Narration
At this home in London lives a man who believes he’s cured his wife of an incurable disease.

Dr David Wheldon
I don’t like using the word ‘cure’ because it’s sort of tempting providence, but I feel in my heart of hearts that the disease has gone.

Sarah Longlands
If it wasn’t for David I would be probably dead or curled up in a corner of a nursing home, useless to the world.

Dr David Wheldon
Well, meet the artist, Sarah.

Sarah Longlands
Hello.

Dr Maryanne Demasi
Hi Sarah, how are you doing?

Narration
Sarah, a talented artist, was diagnosed with MS in her twenties.

Sarah Longlands
My right arm started to go numb and I couldn't use it at all, it was just hanging in front of me.

Dr David Wheldon
Sarah was told that there was absolutely nothing that medicine could do for her. I, I was filled with fear. Here was a person I’d married – an alert, intelligent, bright, creative person, who, to be quite blunt, was, was losing her mind.

Narration
It’s widely accepted that MS is an auto-immune disease. The body’s immune system destroys the myelin sheath around nerve fibres. Patients develop lesions in the brain and spinal cord, and eventually lose their ability to think and move.

Dr Maryanne Demasi
So this is, this is essentially damage in the brain?

Dr David Wheldon
It’s damage, yes.

Narration
David, an expert in infectious diseases who used to treat MS patients, drew on all his experience to formulate a revolutionary theory. He believed that Sarah’s MS was triggered by an infection. The bacterium he honed in on was called Chlamydia Pneumoniae.

Dr David Wheldon
When one thinks of Chlamydia, one automatically thinks of venerally transmitted Chlamydia. Chlamydia Pneumoniae is a respiratory pathogen. It’s spread by droplet infection – coughing and sneezing.

Narration
Infection is so common that it’s likely you’ve been exposed by the age of twenty. The bacteria finds shelter inside blood vessels and nerves, causing low-grade infection over decades. Convinced that Sarah’s body was under attack from this bacterium, David worked tirelessly to find a solution. Together with a colleague in the US, he formulated a cocktail of antibiotics to eradicate this insidious bacterium.

Dr David Wheldon
It’s been shown that a single antibiotic doesn’t eradicate the organism, and these three antibiotics work together in a very specific way.

Dr Maryanne Demasi
How long does the treatment go for?

Dr David Wheldon
I think the treatment should be for a minimum of a year.

Dr Maryanne Demasi
A year?

Dr David Wheldon
Yes.

Dr Maryanne Demasi
That’s a long time on antibiotics.

Dr David Wheldon
It, it is a long time, but it’s a very, very difficult organism to eradicate.

Narration
Sarah’s neurologist insisted she would never regain her function. But David showed me the lesions on Sarah’s MRI scans before and after treatment. The results were nothing short of miraculous.

Dr David Wheldon
I’ve never seen anything like it before. Some lesions have quite literally vanished. Sarah had been numb from the waist down and literally couldn't feel her legs. Sensation came back fairly quickly, in, in, in five or six months.

Dr Maryanne Demasi
Did this shock the neurologists?

Dr David Wheldon
Ah, the neurologist wouldn't see the scan. He says, he says, ‘I’m not looking.’

Dr Maryanne Demasi
So did this, did this surprise you?

Dr David Wheldon
It absolutely shocked me. I think very few people know about the possibility of a chlamydial causation of MS, and therefore very few people will understand the possibility of treatment. The ignorance about this organism is immense.

Narration
The problem is, this bacterium is notoriously difficult to detect in patients. Only a few labs in the world have the expertise.

Dr David Wheldon
Technique is a limiting factor, and to say you don’t isolate something as difficult as this is, like I say, if you search a haystack for ten minutes and say, ‘I see no needle’, really you’re not telling anyone very much.

Dr Maryanne Demasi
This kind of paradigm change in the way we understand and treat disease often causes dissention among the ranks. And this wouldn't be the first time that a radical theory was dismissed by mainstream medicine.

Narration
Australian scientists, Warren and Marshall, went to extraordinary lengths to prove that stomach ulcers were not caused by stress, but by a bacterial infection. Marshall took the ultimate leap of faith and infected himself with the bug.

Barry Marshall
I said to my wife, ‘I took the bacteria, I’ve got the illness.’ And she said, ‘You did what?’

Narration
Fortunately a simple course of antibiotics cured him. The pair won a Nobel Prize in 2005.

Similarly in 2008, Italian doctor Paolo Zamboni was ridiculed when he proposed a whole new approach to MS. He claimed that instead of treating nerve damage, doctors should be focused on blood vessels. He believed that MS was due to a narrowing of the veins in the neck. Zamboni’s theory gave hope to millions of MS sufferers, but many neurologists scoffed at the idea – including Vicki’s.

Vicki Robinson
He was very dismissive, just didn’t feel that it had anything to do with MS, and that was the end of the conversation.

Dr Maryanne Demasi
How did that make you feel?

Vicki Robinson
I was really angry, actually.

Dr Paul Thibault
The good news is that the flow on the right side is still very good.

Narration
So Vicki turned to Australian vein specialist Dr Paul Thibault, who says in his experience with MS patients, Zamboni’s theory has credibility.

Dr Paul Thibault
The veins have been known to be involved in Multiple Sclerosis since the disease was first described in the nineteenth century. But this fact has really been ignored by the neurologists in particular.

Narration
Dr Thibault encouraged Vicki to have the controversial procedure called ‘venoplasty’ to correct the narrowing in her neck veins. The results were virtually instantaneous.

Vicki Robinson
The first thing that I noticed was my eyesight – amazing, just incredible. From pre-procedure in the waiting bay, couldn't read the signs on the wall, to coming out and being placed in the same bay and wow, there they were. Everything clear as a bell.

This is my mobility scooter that I used to have to use to go out anywhere – shopping, any of those sorts of things, before I had the venoplasty. Happily sitting here gathering dust now.

Dr Maryanne Demasi
So your neurologist doesn’t know you’ve had a venoplasty done?

Vicki Robinson
No, no.

Dr Maryanne Demasi
So what does he attribute this miraculous improvement to?

Vicki Robinson
Oh, some patients for some reason just do better than others, and I just happened to be one of those, perhaps.

Narration
It has to be said that not all patients have had the same success as Vicki, and there’s a fifty per cent chance that her veins will narrow again. Dr Thibault agrees with Zamboni that MS is a vascular condition. But he also believes that narrowed veins are caused by a chronic infection, and like David Wheldon, his focus is on Chlamydia Pneumoniae.

Dr Paul Thibault
CPN is on my hit list because it is the bacteria that fits all the requirements. It is known to affect the lining of blood vessels and in particular, veins. It is known to involve the nervous system, is able to cause immune effects. So it fits all the features that we actually see in the symptomatology of MS.

Narration
If you want epidemiological proof that MS is caused by an infection, you only have to look at the isolated population on the Faroe Islands.

Dr Paul Thibault
Prior to World War Two, there was no instance of MS in those islands. In 1940 the islands were occupied by British troops, and by 1945 there was a small epidemic of MS in the islands.

Narration
From this it was postulated that British troops brought MS to the island, but if infection with Chlamydia Pneumoniae is so common, why doesn’t everyone develop MS?

Dr Paul Thibault
Some other factor, like it could be low vitamin D levels, or genetic predisposition, makes them develop the secondary or persistent form of the disease, which affects the neurological tissues and the veins. I don't know why the neurologists aren’t offering them at least Minocycline which has been shown in a number of studies to benefit MS.

Dr Maryanne Demasi
Why, why are neurologists turning their back on this?

Dr Paul Thibault
I think the neurologists have gone down this track for many years and they would have trouble admitting that they may have gone the wrong way. And therefore they continue on with the same line of thought.

Narration
For a neurologist’s perspective, I visited respected MS researcher Associate Professor Robert Heard.

Assoc Prof Robert Heard
We’d love to see more data about it but …

Narration
In a candid moment he did admit that Dr Thibault’s theory was plausible.

Assoc Prof Robert Heard
In an unguarded moment, maybe after a drink or two, a couple of neurologists might say to each other, ‘You know, it just has to be an infection, doesn’t it?’ And in fact I’ve had that exact conversation with well-known MS specialists. But we just can't put our finger on it.

Narration
But despite the anecdotal evidence, Dr Heard warns that responsible treatment is all about evidence-based medicine.

Assoc Prof Robert Heard
If we’re going to do experiments in patients, we’re going to use them as guinea-pigs, we need to have that clinical trial informed by some solid science.

Narration
But clinical trials to obtain solid science requires funding, and getting it is virtually impossible. Why haven’t the clinical trials been done?

Dr Paul Thibault
The problem is that the antibiotics used have been around for many, many years. They’re all off patent, they are inexpensive, and there is no profit in it.

Narration
So as the debate rages on, what hope is there for MS sufferers?

Dr Paul Thibault
We’re looking at treating the cause of the disease, and therefore, if we can get patients early enough, we could cure MS.

Narration
But it’s this sort of statement that worries neurologists.

Assoc Prof Robert Heard
I think people have used the C-word and talked about cures for as long as MS has existed. And I think to use the word ‘cure’ at this stage of our scientific understanding is highly irresponsible.

Narration
Dr Thibault has decided to put Vicki on antibiotics to see if she makes further progress. Like Vicki, David Wheldon knows that clinical trials will take time, and it’s time that MS patients can't afford.

Dr David Wheldon
The clinical trials are not there. It’s … that has to be said, it’s, um, and I wasn’t going to wait for them either, you know. I’d be a widower now if I was waiting for, for clinical trials. Sorry.

Narration
It may be too early to tell if we stand before a cure for MS, but if we do, these men will be remembered as the pioneers.
Topics: Health

Reporter: Dr Maryanne Demasi
Producer: Dr Maryanne Demasi
Researcher: Dr Maryanne Demasi
Camera: Kevin May
Greg Heap
Sound: Stephen Ravich
Adam Toole

Editor: Andrew Glover

Graphics
Toby Goulding
TimeLapse Vision Inc


Story Contacts
Ass Prof Robert Heard
Neurologist
Gosford, NSW
David Wheldon
Microbiologist
Bedford, UK
Dr Paul Thibault
Phlebologist
Central Vein & Cosmetic Medical Centre
Broadmeadow, NSW
Related Info
Multiple Sclerosis Australia
Chlamydia Pneumoniae – more info
Westmead Millenium Institute
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Jatta1001
Viestit:858
Liittynyt:Su Helmi 17, 2013 16:59
Paikkakunta:Pyhtää

Re: MS-tauti infektion aiheuttama?

Viesti Kirjoittaja Jatta1001 » Pe Tammi 18, 2019 14:45

Jo vuosikymmeniä sitten MS-tauti on liitetty borrelia infektioon mutta tämäkin tieto on "hyllytetty".

Multippeliskleroosin, MS-tauti, Historia Ja Sen Linkit Borrelia-Infektioihin.
https://www.prohealth.com/…/history-mul ... rosis-link

Jatta1001
Viestit:858
Liittynyt:Su Helmi 17, 2013 16:59
Paikkakunta:Pyhtää

Re: MS-taudin todennäköinen tarttuva alkuperä, borrelioosi mainittu

Viesti Kirjoittaja Jatta1001 » Ke Syys 20, 2023 12:27

https://www.mdpi.com/2673-4087/4/3/19?f ... YrRbGxdgzs

Multippeliskleroosin todennäköinen tarttuva alkuperä
kirjoittaja Remi L. Landry1,2jaMonica E. Embers1,2,*

Trooppisen lääketieteen laitos, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA

Division of Immunology, Tulane National Primate Research Center, Tulane University Health Sciences, Covington, LA 70433, USA
Vastaanotettu: 18.7.2023 / Tarkistettu: 17. elokuuta 2023 / Hyväksytty: 25.8.2023 / Julkaistu: 7.9.2023

Abstrakti
Multippeliskleroosi (MS) on immuunitulehduksellinen sairaus, joka aiheuttaa keskushermoston valkoisen aineen demyelinisaatiota. On yleisesti hyväksyttyä, että MS-taudin etiologia on monitekijäinen ja että sen uskotaan olevan monimutkainen vuorovaikutus geneettisen alttiuden, ympäristötekijöiden ja tartuntatekijöiden välillä. Vaikka MS-taudin tarkkaa syytä ei vieläkään tunneta, yhä useammat todisteet viittaavat siihen, että taudin kehittyminen on seurausta geneettisesti herkkien yksilöiden ja ympäristön välisistä vuorovaikutuksista, jotka johtavat immuunijärjestelmän häiriöihin ja keskushermoston tulehdukseen. Geneettiset tekijät eivät yksinään riitä aiheuttamaan MS-tautia, ja myös ympäristötekijöillä, kuten virusinfektioilla, tupakoinnilla ja D-vitamiinin puutteella, on tärkeä rooli taudin kehittymisessä. Useita taudinaiheuttajia on liitetty MS-taudin etiologiaan, mukaan lukien Epstein-Barr-virus,Helicobacter pylori , Chlamydia pneumoniae ja Borrelia burgdorferi. Vaikka virukset ja bakteerit ovat hyvin erilaisia, ne voivat manipuloida isäntägeenin ilmentymistä aiheuttaen immuunijärjestelmän häiriöitä, myeliinin tuhoutumista ja hermotulehdusta. Tämä katsaus korostaa patogeenisiä laukaisimia, jotka tulisi ottaa huomioon MS-taudin etenemisessä.
Avainsanat:multippeliskleroosi ; Epstein-Barr-virus (EBV) ; ihmisen herpesvirus 6 ; varicella zoster -virus ; sytomegalovirus ; Helicobacter pylori ; Chlamydia pneumoniae ; Borrelia burgdorferi ; hermoston tulehdus
1. Esittely
Keskushermoston (CNS) kroonisista neurodegeneratiivisista sairauksista multippeliskleroosi (MS) on yksi yleisimmistä. Multippeliskleroosi on krooninen demyelinisoiva autoimmuunisairaus, jota esiintyy noin 2,8 miljoonassa yksilössä maailmanlaajuisesti, ja sen syytä ei vielä tunneta [ 1 ]. MS-taudin ilmaantuvuus ja esiintyvyys vaihtelee merkittävästi eri väestöryhmien ja maantieteellisten alueiden välillä. MS-tauti on yleisin pohjoiseurooppalaisista syntyperäisistä ihmisistä, ja sen esiintyvyyden arvioidaan olevan noin 100–150 tapausta 100 000 ihmistä kohden [ 1 ]. Sitä vastoin MS-tauti on paljon harvinaisempi afrikkalaisilla, aasialaisilla ja latinalaisamerikkalaisilla sukujuurilla, ja arvioitu esiintyvyys on 8–10 tapausta 100 000 ihmistä kohden näissä populaatioissa [ 1]. Maailmanlaajuisesti MS-tautia esiintyy eniten naisilla, ja naisilla on kaksi kertaa suurempi todennäköisyys sairastua MS-tautiin. Joissakin maissa MS-tautia sairastavien naisten ja miesten suhde on jopa 4:1 [ 1 ]. Syitä näihin eroihin MS-tautien esiintyvyydessä ei vielä täysin ymmärretä, mutta uskotaan, että sekä geneettisillä että ympäristötekijöillä on merkitystä.
MS-taudin puhkeaminen ja eteneminen vaihtelee henkilöittäin, mikä tarkoittaa, että se on heterogeeninen sairaus, joka edellyttää vaikuttavien tekijöiden synteesiä. MS-taudin indikaatioita ovat heikentynyt motorinen toiminta, väsymys, silmien liikehäiriöt, kognitiiviset heikkeneminen, ataksia ja dementia.

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